– Immune monitoring of tumor microenvironment can provide insight of immune mechanism into response and immunity of various cancer treatments, but with current immuno-monitoring techniques there are difficulties in clinical application. This is because important issues remain, such as the diversity of cancer, the sample evaluation of limited tissues, changes in the immune ‘hot’ or ‘cold’ tumor microenvironment, comparisons between new and stored tissues, and the evaluation methods of various markers. Although recent anti-cancer immunotherapy has successfully helped treat cancer, and intracellular mechanisms to control the response and resistance of treatment are being studied intensively, anti-cancer immuno-researching requires a comprehensive analysis to understand the complexity of the cell level in the tumor microenvironment since the treatment outcome may vary due to cancer, immune cells, biomarkers, and biological environments.
As advanced platform for understanding complex immune systems, Multiplex IHC for tissue analysis, Cy-TOF, which can measure all immune cells in tissues and blood at once, and ultra-sensitive digital ELISA equipment capable of high sensitivity and full automatic analysis of biomarkers and cytokine secreted from immune cells are essential. It is starting to build an immune monitoring platform internationally and is the only domestic head office.